Guided Annotation and KIDScore

Guided Annotation in synergy with KIDScore optimally supports your consistent embryo evaluation process.

Benefits of KIDScore

• • Improves the decision-making process
• • Enhances consistency
• • Helps you obtain better results

KIDScore™ decision support tool

KIDScore assigns an objective score to each embryo. The scores reflect implantation potential and provide consistent and effective support for embryo selection.

KIDScore for transfer on Day 3 or Day 5

The KIDScore decision support tool is developed by analysing the world’s largest database of embryo development with known clinical outcome. The models are developed by analysing how embryo morphokinetics, cleavage patterns and morphology correlates with implantation outcome after transfer.

Principles of KIDScore D3

Enjoy immediate benefits of time-lapse-based embryo analysis

• • Improved consistency of evaluation and lower interobserver variability5
• • Uses ‘easy-to-annotate’ variables
• • Based on Known Implantation Data (KID) from the day of transfer
• • A powerful tool when you have more embryos available than planned for transfer
• • Designed to predict implantation

KIDScore D3

When to use it

• • When deciding between embryos that reach expected stage on day 3
• • When D3 SET is preferred

How does it work?

KIDScore D3 assigns a morphokinetic score from 1-5 to your annotated embryos. The score from 1-5 is a relative measure of the implantation potential of the embryo. The following variables need to be annotated in accordance with specific guidelines: PN assessment, PN fading, time (t) to 2, 3, 4, 5 and 8 cells.

KIDScore D3 & implantation data

The chart represents unselected embryos, embryos chosen for transfer, implanted embryos and embryos resulting in a live birth from cycles where known outcome data is available. The distribution of embryos across score groups is shown. This indicates that there is excellent concordance between the model and embryos with high implantation potential.

KIDScore D5

When to use it?

• • When more good quality blastocysts are available than are planned for transfer
• • When deciding which embryos are suitable for biopsy or diagnosis

How does it work?

KIDScore D5* considers the morphology and the morphokinetic traits of an embryo. For each embryo the model calculates a continuous score from 1-9.9. The score reflects the statistical chance of implantation based on development information from the five-day culture period. The higher the score, the greater the statistical chance of implantation. Only a few annotations are required to obtain a score, which further improves the worfklow.

KIDScore D5 & implantation data

KIDScore D5 scores show an increased relative implantation with higher scores. The model is based on a large database of KID blastocysts originating from a wide range of IVF clinics.

*KIDScore D5 can only be used when culturing under reduced oxygen conditions.

We have seen improved IVF outcomes since we introduced EmbryoScope time-lapse system in 2013. We owe it to our patients to use time-lapse - to give them the best possible result.

- Helen Hunter, principal embryologist, Department of Reproductive Medicine, Saint Mary's Hospital, Manchester, UK