G-1™
G-1™ PLUS and G-1™ provides the carbohydrates, amino acids and hyaluronan needed to support the embryo during the first critical stages of development.
Description : G-1 PLUS and G-1 are bicarbonate buffered media containing hyaluronan. G-1 PLUS also contains human serum albumin.
Purpose : Medium for culture of embryos from the pronucleate stage to day 2 or day 3.
Storage : Store dark at +2 to +8°C
IMPORTANT NUTRIENTS SUPPORTS THE EMBRYO
G-1 PLUS and G-1 are two different media for culture of human embryos from after fertilisation until the 8-cell stage. G-1 PLUS is supplemented with human serum albumin, HSA, and is ready to use. G-1 must be supplemented with G-MM™ or HSA-solution™.
Both media contains amino acids to support embryo viability and hyaluronan to improve development and cryosurvivability and to facilitate implantation. They also contain lipoic acid as antioxidant to protect the embryo against reactive oxygen species during culture in vitro.
Optimise all the way with G-Series
Ensure optimal conditions before, during and after culture by using the whole G-Series. All G-Series media share the same basic composition to secure viability and implantation potential. Osmolality, pH and supporting compounds are all kept constant. This foundation prevents intracellular stresses as the embryos progress through the IVF process.
G-Series - confidence at each step
Each product in the G-Series™ is developed to resemble conditions in the female reproductive tract and fulfil embryo requirements.
HOW TO USE THIS PRODUCT
Additional documents
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G-1™Scientific summaries |
G-Series culture media improve blastocyst development
Data from two studies presented at Annual Meeting of the Japanese Society of Clinical Embryologist show that good quality embryo rate and blastocyst development can be improved when using G-Series culture media (G-IVF, G-1 and G-2) from Vitrolife compared to a HTF-based non-hyaluronan containing media.
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G-1™Scientific summaries |
G-Series culture media shown to increase blastocyst development compared to control
In a study by Matsuoka et al, embryo culture was done either Vitrolife’s G-Series™ culture media or a mix of sequential culture media (control). The results show that good-quality blastocyst development was more frequent after culture in G-Series media containing hyaluronan.
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G-1™Scientific summaries |
Optimised clinical outcomes with blastocyst culture and cryopreservation using Vitrolife G-Series culture media
A study by Zhu et al demonstrate that extended culture before cryopreservation allows for selection of viable embryos with a high chance of implantation after warming. The high blastocyst formation rate (73.8%) using Vitrolife culture media, together with an efficient cryopreservation program resulting in survival rates of >96% should eliminate any earlier concerns about blastocyst culture and cryopreservation.
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G-1™Scientific summaries |
Embryo culture in G-Series results in significantly higher cell numbers and implantation rates compared to culture in HTF
A study by Kleijkers show that besides cell numbers and implantations rates, gene expression and certain pathways in preimplantation embryos are also affected by culture medium.
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